Gestational valproate alters BOLD activation in response to complex social and primary sensory stimuli.

Valproic acid (VPA) has been used clinically as an anticonvulsant medication during pregnancy; however, it poses a neurodevelopmental risk due to its high teratogenicity. We hypothesized that midgestational (GD) exposure to VPA will lead to lasting deficits in social behavior and the processing of s...

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Bibliographic Details
Main Authors: Ada C Felix-Ortiz, Marcelo Febo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3355108?pdf=render