Angiogenic and Osteogenic Coupling Effects of Deferoxamine-Loaded Poly(lactide-co-glycolide)-Poly(ethylene glycol)-Poly(lactide-co-glycolide) Nanoparticles

Angiogenic and Osteogenic Coupling Effects of Deferoxamine-Loaded Poly(lactide-co-glycolide)-Poly(ethylene glycol)-Poly(lactide-co-glycolide) Nanoparticles

Angiogenesis and osteogenesis coupling processes are essential for bone regeneration, and human bone marrow stromal cells (hBMSCs) along with endothelial cells (ECs) are crucial participants. Deferoxamine (DFO), a hypoxia-mimetic agent, could activate the hypoxia-inducible factor (HIF)-1α signaling...

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Bibliographic Details
Main Authors:	Manle Qiu, Chongyang Wang, Daoyun Chen, Chaoyong Shen, Huakun Zhao, Yaohua He
Format:	Article
Language:	English
Published:	MDPI AG 2016-10-01
Series:	Applied Sciences
Subjects:	PLGA-PEG-PLGA nanoparticles deferoxamine drug delivery system angiogenesis osteogenesis
Online Access:	http://www.mdpi.com/2076-3417/6/10/290

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