A mouse model for binge-level methamphetamine use

A mouse model for binge-level methamphetamine use

Binge/crash cycles of methamphetamine (MA) use are frequently reported by individuals suffering from MA use disorders. An MA binge is self-reported as multiple daily doses that commonly accumulate to 800 mg/day (~10 mg/kg/day for a 170 pound human). A genetic animal model with a similar vulnerabilit...

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Bibliographic Details
Main Authors: Shkelzen Shabani, Sydney K Houlton, Laura Hellmuth, Erika Mojica, John R.K. Mootz, Zhen Zhu, Cheryl Reed, Tamara J Phillips
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Neuroscience
Subjects:
Addiction
self-administration
psychostimulant
withdrawal
genetic
Abstinence
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00493/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00493/full

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