Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription

Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription

The molecular mechanisms of memory storage remain poorly understood. In this study, authors describe a new mechanism that regulates the cellular patterns of early response gene signaling during learning via the recruitment of two functionally redundant nuclear repressors, class IIa histone deacetyla...

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Bibliographic Details
Main Authors: Yongchuan Zhu, Min Huang, Eric Bushong, Sebastien Phan, Marco Uytiepo, Elizabeth Beutter, Daniel Boemer, Kristin Tsui, Mark Ellisman, Anton Maximov
Format: Article
Language:English
Published: Nature Portfolio 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11409-0

Internet

https://doi.org/10.1038/s41467-019-11409-0

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