Deconvolution of intergenic polymorphisms determining high expression of Factor H binding protein in meningococcus and their association with invasive disease.

Deconvolution of intergenic polymorphisms determining high expression of Factor H binding protein in meningococcus and their association with invasive disease.

Neisseria meningitidis is a strictly human pathogen and is the major cause of septicemia and meningitis worldwide. Factor H binding protein (fHbp) is a meningococcal surface-exposed lipoprotein that binds the human Complement factor H allowing the bacterium to evade the host innate immune response....

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Bibliographic Details
Main Authors: Marco Spinsanti, Tarcisio Brignoli, Margherita Bodini, Lucia Eleonora Fontana, Matteo De Chiara, Alessia Biolchi, Alessandro Muzzi, Vincenzo Scarlato, Isabel Delany
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009461&type=printable

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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009461&type=printable

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