Immunological non-inferiority of a new fully liquid presentation of the MenACWY-CRM vaccine to the licensed vaccine: results from a randomized, controlled, observer-blind study in adolescents and young adults

Immunological non-inferiority of a new fully liquid presentation of the MenACWY-CRM vaccine to the licensed vaccine: results from a randomized, controlled, observer-blind study in adolescents and young adults

A fully liquid MenACWY-CRM vaccine presentation has been developed, modifying the meningococcal serogroup A (MenA) component from lyophilized to liquid. The safety and immunogenicity of the liquid presentation at the end of the intended shelf-life (aged for 24 or 30 months) were compared to the lice...

Full description

Bibliographic Details
Main Authors: Javier Díez-Domingo, Juan Carlos Tinoco, Airi Poder, Ener Cagri Dinleyici, Haylene Nell, Ignacio Salamanca de la Cueva, Tolga Ince, Edson Duarte Moreira, Khatija Ahmed, Kleber Luz, Yulia Kovshirina, Carlos Eduardo Medina Pech, Tauseefullah Akhund, Valerio Romolini, Marco Costantini, Thembile Mzolo, Barry Kunnel, Isabelle Lechevin, Marianna Aggravi, Paola Tiberi, K Narendran, Juan-Antonio García-Martínez, Venere Basile, Elena Fragapane, Maria Lattanzi, Michele Pellegrini
Format: Article
Language:English
Published: Taylor & Francis Group 2022-01-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
menacwy-crm
meningococcal serogroup a
human serum bactericidal assay
non-inferiority
adolescents
Online Access:http://dx.doi.org/10.1080/21645515.2021.1981085

Internet

http://dx.doi.org/10.1080/21645515.2021.1981085

Similar Items