Specific lncRNA signatures discriminate childhood acute leukaemias: a pilot study

Specific lncRNA signatures discriminate childhood acute leukaemias: a pilot study

Abstract Background Long non-coding RNAs are RNAs longer than 200 bps that do not encode any proteins and are able to alter gene expression by acting on different steps of regulation, including DNA methylation and chromatin structure. They represent a class of biomarkers of crescent interest in the...

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Main Authors: Lorena Buono, Concetta Iside, Antonia De Matteo, Pio Stellato, Giuliana Beneduce, Roberta Penta de Vera d’Aragona, Rosanna Parasole, Marco Salvatore, Giovanni Smaldone, Peppino Mirabelli
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Cancer Cell International
Subjects:
T-ALL
B-ALL
lncRNA
Transcriptome
Leukaemia
Biomarkers
Online Access:https://doi.org/10.1186/s12935-022-02789-3

Internet

https://doi.org/10.1186/s12935-022-02789-3

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