The Mycobacterium tuberculosis methyltransferase Rv2067c manipulates host epigenetic programming to promote its own survival

The Mycobacterium tuberculosis methyltransferase Rv2067c manipulates host epigenetic programming to promote its own survival

Abstract Mycobacterium tuberculosis has evolved several mechanisms to counter host defense arsenals for its proliferation. Here we report that M. tuberculosis employs a multi-pronged approach to modify host epigenetic machinery for its survival. It secretes methyltransferase (MTase) Rv2067c into mac...

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Bibliographic Details
Main Authors: Prakruti R. Singh, Venkatareddy Dadireddy, Shubha Udupa, Shashwath Malli Kalladi, Somnath Shee, Sanjeev Khosla, Raju S. Rajmani, Amit Singh, Suryanarayanarao Ramakumar, Valakunja Nagaraja
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43940-6

Internet

https://doi.org/10.1038/s41467-023-43940-6

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