Muscle progenitor cells are required for skeletal muscle regeneration and prevention of adipogenesis after limb ischemia

Muscle progenitor cells are required for skeletal muscle regeneration and prevention of adipogenesis after limb ischemia

Skeletal muscle injury in peripheral artery disease (PAD) has been attributed to vascular insufficiency, however evidence has demonstrated that muscle cell responses play a role in determining outcomes in limb ischemia. Here, we demonstrate that genetic ablation of Pax7+ muscle progenitor cells (MPC...

Full description

Bibliographic Details
Main Authors: Hasan Abbas, Lindsey A. Olivere, Michael E. Padgett, Cameron A. Schmidt, Brian F. Gilmore, Timothy J. McCord, Kevin W. Southerland, Joseph M. McClung, Christopher D. Kontos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
peripheral artery disease
critical limb threatening ischemia
muscle progenitor cells
skeletal muscle regeneration
fibro/adipogenic progenitor cells
hind limb ischemia
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1118738/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1118738/full

Similar Items