Unmasking GluN1/GluN3A excitatory glycine NMDA receptors

Excitatory glycine GluN1/GluN3A receptors are atypical NMDARs that have been difficult to study. Here the authors identify new properties of these receptors, including potentiation by the GluN1 antagonist CGP-78608 that allows detection of functional GluN1/GluN3A receptors in the juvenile brain.

Bibliographic Details
Main Authors: Teddy Grand, Sarah Abi Gerges, Mélissa David, Marco A. Diana, Pierre Paoletti
Format: Article
Language:English
Published: Nature Portfolio 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07236-4