A yeast‐based tool for screening mammalian diacylglycerol acyltransferase inhibitors

Abstract Dysregulation of lipid metabolism is associated with obesity and metabolic diseases but there is also increasing evidence of a relationship between lipid body excess and cancer. Lipid body synthesis requires diacylglycerol acyltransferases (DGATs) which catalyze the last step of triacylglyc...

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Bibliographic Details
Main Authors: Peter Gajdoš, Rodrigo Ledesma‐Amaro, Jean‐Marc Nicaud, Tristan Rossignol
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:MicrobiologyOpen
Subjects:
Online Access:https://doi.org/10.1002/mbo3.1334