A yeast‐based tool for screening mammalian diacylglycerol acyltransferase inhibitors
Abstract Dysregulation of lipid metabolism is associated with obesity and metabolic diseases but there is also increasing evidence of a relationship between lipid body excess and cancer. Lipid body synthesis requires diacylglycerol acyltransferases (DGATs) which catalyze the last step of triacylglyc...
Main Authors: | Peter Gajdoš, Rodrigo Ledesma‐Amaro, Jean‐Marc Nicaud, Tristan Rossignol |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-12-01
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Series: | MicrobiologyOpen |
Subjects: | |
Online Access: | https://doi.org/10.1002/mbo3.1334 |
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