Chromosomal localization of cohesin is differentially regulated by WIZ, WAPL, and G9a

Abstract Background The cohesin complex is essential for proper chromosome structure and gene expression. Defects in cohesin subunits and regulators cause changes in cohesin complex dynamics and thereby alter three-dimensional genome organization. However, the molecular mechanisms that drive cohesin...

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Bibliographic Details
Main Authors: Megan Justice, Audra F. Bryan, Juanita C. Limas, Jeanette Gowen Cook, Jill M. Dowen
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-022-08574-w