Reverse-Phase Chromatographic Determination and Intrinsic Stability Behavior of 5-[(4-Chlorophenoxy)Methyl]-1,3,4-Oxadiazole-2-Thiol

Reverse-Phase Chromatographic Determination and Intrinsic Stability Behavior of 5-[(4-Chlorophenoxy)Methyl]-1,3,4-Oxadiazole-2-Thiol

The study describes the development and preliminary validation of a simple reverse-phase chromatographic method for determination of a novel drug candidate, 5-[(4-chlorophenoxy) methyl]-1,3,4-oxadiazole-2-thiol (OXCPM), in bulk and stressed solution, in order to find out the intrinsic stability beha...

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Bibliographic Details
Main Authors: Shehzadi Naureen, Hussain Khalid, Islam Muhammad, Bukhari Nadeem Irfan, Khan Muhammad Tanveer, Salman Muhammad, Siddiqui Sabahat Zahra, Rehman Aziz-Ur, Abbasi Muhammad Athar
Format: Article
Language:English
Published: Sciendo 2018-12-01
Series:Acta Pharmaceutica
Subjects:
5-[(4-chlorophenoxy)methyl]-1,3,4-oxadiazole-2-thiol
forced degradation
stability
rp-hplc/dad
Online Access:https://doi.org/10.2478/acph-2018-0036

Internet

https://doi.org/10.2478/acph-2018-0036

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