Exosome-drug conjugates delivery: a promising strategy for ameliorating the pharmacokinetic profile of artesunate

Exosome-drug conjugates delivery: a promising strategy for ameliorating the pharmacokinetic profile of artesunate

Artesunate (ATS) is considered the most widely employed artemisnin derivative in the treatment of Plasmodium falciparum malaria. However, poor solubility and low bioavailability of ATS limit its further clinical application. Herein, we developed a new strategy based on the exosome (exo) - drug conju...

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Bibliographic Details
Main Authors: Da Wang, Yunfei Bai, Guogang Cheng, Shengqiang Shen, Gengwu Xiao, Demei Ma, Ganggang Zhao, Wei Chen, Tianshi Li, Litao Zhang, Xiaohu Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
exosomes
artesunate
bio-conjugation
delivery
pharmacokinetic
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1437787/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2024.1437787/full

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