Seed amplification assays for diagnosing synucleinopathies: the issue of influencing factors

Seed amplification assays for diagnosing synucleinopathies: the issue of influencing factors

Background: The prion-like misfolding and aggregation of α-synuclein (α-syn) is involved in the pathophysiology of Parkinson’s disease and other synucleinopathies. Seed amplification assays (SAAs) are biophysical tools that take advantage on the peculiar properties of prion proteins by amplifying sm...

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Bibliographic Details
Main Authors: Giovanni Bellomo, Silvia Paciotti, Leonardo Gatticchi, Domenico Rizzo, Federico Paolini Paoletti, Marco Fragai, Lucilla Parnetti
Format: Article
Language:English
Published: IMR Press 2021-11-01
Series:Frontiers in Bioscience-Landmark
Subjects:
α-synuclein
pmca
rt-quic
saas
influencing factors
Online Access:https://www.imrpress.com/journal/FBL/26/11/10.52586/5010

Internet

https://www.imrpress.com/journal/FBL/26/11/10.52586/5010

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