Keeping up with the guidelines: design changes to the STREAM stage 2 randomised controlled non-inferiority trial for rifampicin-resistant tuberculosis

Keeping up with the guidelines: design changes to the STREAM stage 2 randomised controlled non-inferiority trial for rifampicin-resistant tuberculosis

Abstract Results from the STREAM stage 1 trial showed that a 9-month regimen for patients with rifampicin-resistant tuberculosis was non-inferior to the 20-month regimen recommended by the 2011 WHO treatment guidelines. Similar levels of severe adverse events were reported on both regimens suggestin...

Full description

Bibliographic Details
Main Authors: Ruth L. Goodall, Karen Sanders, Gay Bronson, Meera Gurumurthy, Gabriela Torrea, Sarah Meredith, Andrew Nunn, I. D. Rusen, on behalf of the STREAM Trial Team
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Trials
Subjects:
Trial
Design
Rifampicin resistance tuberculosis
Online Access:https://doi.org/10.1186/s13063-022-06397-4

Internet

https://doi.org/10.1186/s13063-022-06397-4

Similar Items