LSD1 modulates the bone metastasis of breast cancer cells through hnRNPA2B1-mediated sorting of exosomal miRNAs

LSD1 modulates the bone metastasis of breast cancer cells through hnRNPA2B1-mediated sorting of exosomal miRNAs

Abstract Bone metastasis is a key contributor to morbidity and mortality of breast cancer patients. We have previously shown that exosomal miRNAs derived from LSD1 knockdown (KD) breast cancer cells inhibit osteoblast differentiation and promote osteoclast differentiation. However, how LSD1 regulate...

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Bibliographic Details
Main Authors: Ziyu Liu, Benkai Xin, Nan Zhang, Peipei An, Yueru Shi, Jingtong Yang, Youzhong Wan, Yuquan He, Xin Hu
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01897-5

Internet

https://doi.org/10.1038/s41420-024-01897-5

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