GRP78 modulates cell adhesion markers in prostate Cancer and multiple myeloma cell lines

GRP78 modulates cell adhesion markers in prostate Cancer and multiple myeloma cell lines

Abstract Background Glucose regulated protein 78 (GRP78) is a resident chaperone of the endoplasmic reticulum and a master regulator of the unfolded protein response under physiological and pathological cell stress conditions. GRP78 is overexpressed in many cancers, regulating a variety of signaling...

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Bibliographic Details
Main Authors: Christopher N. Cultrara, Stephen D. Kozuch, Poornema Ramasundaram, Claudia J. Heller, Sunil Shah, Adah E. Beck, David Sabatino, Jenny Zilberberg
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
GRP78
Gene knockdown
Epithelia-mesenchymal transition (EMT)
Cell adhesion
Online Access:http://link.springer.com/article/10.1186/s12885-018-5178-8

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http://link.springer.com/article/10.1186/s12885-018-5178-8

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