Palmitoylethanolamide Mitigates Paclitaxel Toxicity in Primary Dorsal Root Ganglion Neurons

Palmitoylethanolamide Mitigates Paclitaxel Toxicity in Primary Dorsal Root Ganglion Neurons

Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of several chemotherapeutic agents, such as Paclitaxel. The main symptoms of CIPN are pain and numbness in the hands and feet. Paclitaxel is believed to accumulate in the dorsal root ganglia and free nerve endings. Novel thera...

Full description

Bibliographic Details
Main Authors: Amira Elfarnawany, Faramarz Dehghani
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
peripheral neuropathic pain
neurotoxicity
dorsal root ganglion neurons
palmitoylethanolamide
paclitaxel
neurite length
Online Access:https://www.mdpi.com/2218-273X/12/12/1873

Internet

https://www.mdpi.com/2218-273X/12/12/1873

Similar Items