Guiding Hepatic Differentiation of Pluripotent Stem Cells Using 3D Microfluidic Co-Cultures with Human Hepatocytes

Guiding Hepatic Differentiation of Pluripotent Stem Cells Using 3D Microfluidic Co-Cultures with Human Hepatocytes

Human pluripotent stem cells (hPSCs) are capable of unlimited proliferation and can undergo differentiation to give rise to cells and tissues of the three primary germ layers. While directing lineage selection of hPSCs has been an active area of research, improving the efficiency of differentiation...

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Bibliographic Details
Main Authors: Pouria Fattahi, Jose M. de Hoyos-Vega, Jong Hoon Choi, Caden D. Duffy, Alan M. Gonzalez-Suarez, Yuji Ishida, Kianna M. Nguyen, Kihak Gwon, Quinn P. Peterson, Takeshi Saito, Gulnaz Stybayeva, Alexander Revzin
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
microfluidics
co-culture
primary hepatocytes
embryonic stem cells
hepatic differentiation
Online Access:https://www.mdpi.com/2073-4409/12/15/1982

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https://www.mdpi.com/2073-4409/12/15/1982

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