Toosendanin suppresses African swine fever virus replication through upregulating interferon regulatory factor 1 in porcine alveolar macrophage cultures

Toosendanin suppresses African swine fever virus replication through upregulating interferon regulatory factor 1 in porcine alveolar macrophage cultures

African swine fever virus (ASFV) is a highly infectious and lethal swine pathogen that causes severe socio-economic consequences in affected countries. Unfortunately, effective vaccine for combating ASF is unavailable so far, and the prevention and control strategies for ASFV are still very limited....

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Bibliographic Details
Main Authors: Yuanjia Liu, Xinheng Zhang, Zexin Liu, Li Huang, Weixin Jia, Xinlei Lian, Changjiang Weng, Guihong Zhang, Wenbao Qi, Jianxin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Microbiology
Subjects:
African swine fever virus
toosendanin
antiviral activity
porcine alveolar macrophages
interferon regulatory factor 1
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.970501/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.970501/full

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