CpG plus radiotherapy: a review of preclinical works leading to clinical trial

Studies performed 3 decades ago in our laboratory supported the hypothesis that radiation efficacy may be augmented by bacterial extracts that stimulate non-specific systemic antitumor immune responses. Application to the clinic was halted by unacceptable side effects and toxicities resulting from e...

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Bibliographic Details
Main Authors: Kathy A. Mason, Nancy R. Hunter
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00101/full