Targeting M-MDSCs enhances the therapeutic effect of BNCT in the 4-NQO-induced murine head and neck squamous cell carcinoma model

Targeting M-MDSCs enhances the therapeutic effect of BNCT in the 4-NQO-induced murine head and neck squamous cell carcinoma model

PurposeMalignant head and neck squamous cell carcinoma (HNSCC) is characterized by a poor prognosis and resistance to conventional radiotherapy. Infiltrating myeloid-derived suppressive cells (MDSCs) is prominent in HNSCC and is linked to immune suppression and tumor aggressiveness. This study aimed...

Full description

Bibliographic Details
Main Authors: Chun-Hsiang Chang, Chi-Jui Chen, Ching-Fang Yu, Hui-Yu Tsai, Fang-Hsin Chen, Chi-Shiun Chiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
BNCT
MDSCs
4-NQO
CSF-1R inhibitor
HNSCC
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1263873/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1263873/full

Similar Items