Comparative Evaluation of the Antibacterial and Antitumor Activities of 9-Phenylfascaplysin and Its Analogs

Comparative Evaluation of the Antibacterial and Antitumor Activities of 9-Phenylfascaplysin and Its Analogs

Based on the results of our own preliminary studies, the derivative of the marine alkaloid fascaplysin containing a phenyl substituent at C-9 was selected to evaluate the therapeutic potential in vivo and in vitro. It was shown that this compound has outstandingly high antimicrobial activity against...

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Bibliographic Details
Main Authors: Maxim E. Zhidkov, Maria A. Sidorova, Polina A. Smirnova, Oleg A. Tryapkin, Andrey V. Kachanov, Alexey V. Kantemirov, Lyubov G. Dezhenkova, Natalia E. Grammatikova, Elena B. Isakova, Andrey E. Shchekotikhin, Marina A. Pak, Olga N. Styshova, Anna A. Klimovich, Aleksandr M. Popov
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Marine Drugs
Subjects:
fascaplysin derivatives
antibacterial activity
antiproliferative activity
antitumor activity
9-phenylfascaplysin
Online Access:https://www.mdpi.com/1660-3397/22/2/53

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https://www.mdpi.com/1660-3397/22/2/53

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