Implementation research of a cluster randomized trial evaluating the implementation and effectiveness of intermittent preventive treatment for malaria using dihydroartemisinin-piperaquine on reducing malaria burden in school-aged children in Tanzania: methodology, challenges, and mitigation

Implementation research of a cluster randomized trial evaluating the implementation and effectiveness of intermittent preventive treatment for malaria using dihydroartemisinin-piperaquine on reducing malaria burden in school-aged children in Tanzania: methodology, challenges, and mitigation

Abstract Background It has been more than 20 years since the malaria epidemiologic shift to school-aged children was noted. In the meantime, school-aged children (5–15 years) have become increasingly more vulnerable with asymptomatic malaria prevalence reaching up to 70%, making them reservoirs for...

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Bibliographic Details
Main Authors: Geofrey Makenga, Misago D. Seth, Vito Baraka, Bruno P. Mmbando, Daniel P. Challe, Filbert Francis, Athanas Mhina, Daniel T. R. Minja, Mercy Chiduo, Celine Mandara, Edwin Liheluka, Samwel Gesase, Method Segeja, George Mtove, Mathias Kamugisha, Abdallah Lusasi, Frank Chacky, Anna David, Sumaiyya Thawer, Ally Mohamed, Samwel Lazaro, Fabrizio Molteni, Alex Nkayamba, Jean-Pierre Van geertruyden, John P. A. Lusingu
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Malaria Journal
Subjects:
Malaria
Effectiveness
Dihydroartemisinin-piperaquine
Implementation research
Anaemia
Cluster randomized trial
Online Access:https://doi.org/10.1186/s12936-022-04428-8

Internet

https://doi.org/10.1186/s12936-022-04428-8

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