Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models
Mesenchymal stem cells (MSCs) are a potential source of cell-based disease-modifying therapy in Parkinsonian disorders. A promising approach to develop in vitro culture methods that mimic natural MSC niche is cell priming. Uric acid (UA), a powerful antioxidant, scavenges reactive oxygen species, wh...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-03-01
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Series: | Journal of Tissue Engineering |
Online Access: | https://doi.org/10.1177/20417314211004816 |