Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models

Mesenchymal stem cells (MSCs) are a potential source of cell-based disease-modifying therapy in Parkinsonian disorders. A promising approach to develop in vitro culture methods that mimic natural MSC niche is cell priming. Uric acid (UA), a powerful antioxidant, scavenges reactive oxygen species, wh...

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Bibliographic Details
Main Authors: Ha Na Kim, Jin Young Shin, Dong Yeol Kim, Ji Eun Lee, Phil Hyu Lee
Format: Article
Language:English
Published: SAGE Publishing 2021-03-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314211004816