Secreted Phospholipase A<sub>2</sub>-IIA Modulates Transdifferentiation of Cardiac Fibroblast through EGFR Transactivation: An Inflammation–Fibrosis Link

Secreted Phospholipase A<sub>2</sub>-IIA Modulates Transdifferentiation of Cardiac Fibroblast through EGFR Transactivation: An Inflammation–Fibrosis Link

Secreted phospholipase A<sub>2</sub>-IIA (sPLA<sub>2</sub>-IIA) is a pro-inflammatory protein associated with cardiovascular disorders, whose functions and underlying mechanisms in cardiac remodelling are still under investigation. We herein study the role of sPLA<sub>2...

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Bibliographic Details
Main Authors: Ruben Martin, Beatriz Gutierrez, Claudia Cordova, Alberto San Roman, Yolanda Alvarez, Marita Hernandez, Victoria Cachofeiro, Maria L Nieto
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
cardiac fibroblast
epidermal growth factor receptor
lysyl oxidase
fibrosis
myocarditis
secreted phospholipase a<sub>2</sub>
Online Access:https://www.mdpi.com/2073-4409/9/2/396

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https://www.mdpi.com/2073-4409/9/2/396

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