Integrated proteomic and metabolomic profile analyses of cardiac valves revealed molecular mechanisms and targets in calcific aortic valve disease

Integrated proteomic and metabolomic profile analyses of cardiac valves revealed molecular mechanisms and targets in calcific aortic valve disease

BackgroundThis study aimed to define changes in the metabolic and protein profiles of patients with calcific aortic valve disease (CAVD).Methods and resultsWe analyzed cardiac valve samples of patients with and without (control) CAVD (n = 24 per group) using untargeted metabolomics and tandem mass t...

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Bibliographic Details
Main Authors: Bo Fu, Jing Wang, Lianqun Wang, Qiang Wang, Zhigang Guo, Meilin Xu, Nan Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
calcific aortic valve disease
proteomics
metabolomics
cardiac valve
molecular
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.944521/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.944521/full

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