Flow electrosynthesis for efficient O-trifluoromethylation of electron-deficient phenols

A sustainable strategy for O-trifluoromethylation of electron-deficient phenols by combining electrochemical synthesis with flow technology is presented. The reaction is optimized by screening experiments to establish a fast and efficient flow protocol. Simultaneous anodic oxidation of Langlois reag...

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Bibliographic Details
Main Authors: Johannes Bernd, Andreas Terfort
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Electrochemistry Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1388248123001194