Predictive overfitting in immunological applications: Pitfalls and solutions

Overfitting describes the phenomenon where a highly predictive model on the training data generalizes poorly to future observations. It is a common concern when applying machine learning techniques to contemporary medical applications, such as predicting vaccination response and disease status in in...

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Bibliographic Details
Main Authors: Jeremy P. Gygi, Steven H. Kleinstein, Leying Guan
Format: Article
Language:English
Published: Taylor & Francis Group 2023-08-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2023.2251830