DNA Methylation Analysis to Unravel Altered Genetic Pathways Underlying Early Onset and Late Onset Neonatal Sepsis. A Pilot Study

DNA Methylation Analysis to Unravel Altered Genetic Pathways Underlying Early Onset and Late Onset Neonatal Sepsis. A Pilot Study

Background: Neonatal sepsis is a systemic condition widely affecting preterm infants and characterized by pro-inflammatory and anti-inflammatory responses. However, its pathophysiology is not yet fully understood. Epigenetics regulates the immune system, and its alteration leads to the impaired immu...

Full description

Bibliographic Details
Main Authors: Sheila Lorente-Pozo, Paula Navarrete, María José Garzón, Inmaculada Lara-Cantón, Jesús Beltrán-García, Rebeca Osca-Verdegal, Salvador Mena-Mollá, Eva García-López, Máximo Vento, Federico V. Pallardó, José Luis García-Giménez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
neonatology and pediatric intensive care
DNA methylation
sepsis
inflammation
immunosuppression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.622599/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.622599/full

Similar Items