Blockage of Orai1-Nucleolin interaction meditated calcium influx attenuates breast cancer cells growth
Abstract As an important second messenger, calcium (Ca2+) regulates a wide variety of physiological processes. Disturbance of intracellular calcium homeostasis implicated in the occurrence of multiple types of diseases. Orai1 is the major player in mediating store-operated calcium entry (SOCE) and r...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-09-01
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Series: | Oncogenesis |
Online Access: | https://doi.org/10.1038/s41389-022-00429-z |