Using human induced pluripotent stem cell-derived cardiomyocytes to understand the mechanisms driving cardiomyocyte maturation

Using human induced pluripotent stem cell-derived cardiomyocytes to understand the mechanisms driving cardiomyocyte maturation

Cardiovascular diseases are the leading cause of mortality and reduced quality of life globally. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide a personalized platform to study inherited heart diseases, drug-induced cardiac toxicity, and cardiac regenerative therapy....

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Bibliographic Details
Main Authors: Homa Hamledari, Parisa Asghari, Farah Jayousi, Alejandro Aguirre, Yasaman Maaref, Tiffany Barszczewski, Terri Ser, Edwin Moore, Wyeth Wasserman, Ramon Klein Geltink, Sheila Teves, Glen F. Tibbits
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
transcriptional regulation
cell signaling
preterm heart
hiPSC-derived cardiomyocyte
mTOR pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.967659/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.967659/full

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