Modified nusinersen intrathecal injection method: inclusion of a septal needle-free closed infusion connector

Modified nusinersen intrathecal injection method: inclusion of a septal needle-free closed infusion connector

ObjectiveNusinersen, an extremely expensive biologic drug (around 100,000 US$ per dose) that needs to be administered intrathecally, is approved for the treatment of 5q-spinal muscular atrophy (SMA). Because of the low muscle tone of the back muscles of pediatric SMA patients, especially type 1 SMA...

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Bibliographic Details
Main Authors: Yani Zhang, Kelu Zheng, Cuili Liang, Ruidan Zheng, Jinghui Chen, Minyan Jiang, Zhizi Zhou, Yuan Zhao, Min Rao, Sida Yang, Wenxiong Chen, Li Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Neurology
Subjects:
modified
intrathecal injection
infusion connector
nusinersen
spinal muscular atrophy
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1234442/full

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https://www.frontiersin.org/articles/10.3389/fneur.2023.1234442/full

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