Investigating role of ASIC2 in synaptic and behavioral responses to drugs of abuse

Investigating role of ASIC2 in synaptic and behavioral responses to drugs of abuse

Drugs of abuse produce rearrangements at glutamatergic synapses thought to contribute to drug-reinforced behaviors. Acid-Sensing Ion Channels (ASICs) have been suggested to oppose these effects, largely due to observations in mice lacking the ASIC1A subunit. However, the ASIC2A and ASIC2B subunits a...

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Bibliographic Details
Main Authors: Margaret J. Fuller, Subhash C. Gupta, Rong Fan, Rebecca J. Taugher-Hebl, Grace Z. Wang, Noah R. R. Andrys, Amal K. Bera, Jason J. Radley, John A. Wemmie
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
ASIC
ASIC2
cocaine
opioid
morphine
nucleus accumbens
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1118754/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2023.1118754/full

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