Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men.

Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men.

The dominant congenital disorders Apert syndrome, achondroplasia and multiple endocrine neoplasia-caused by specific missense mutations in the FGFR2, FGFR3 and RET proteins respectively-represent classical examples of paternal age-effect mutation, a class that arises at particularly high frequencies...

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Bibliographic Details
Main Authors: Jasmine Lim, Geoffrey J Maher, Gareth D H Turner, Wioleta Dudka-Ruszkowska, Stephen Taylor, Ewa Rajpert-De Meyts, Anne Goriely, Andrew O M Wilkie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3412839?pdf=render

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http://europepmc.org/articles/PMC3412839?pdf=render

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