Case Report: Castleman Disease With an Associated Stromal Spindle Cell Proliferation, PDGFRB Mutation and p53 Expression: Clonal Origins of a Rare Disease

Case Report: Castleman Disease With an Associated Stromal Spindle Cell Proliferation, PDGFRB Mutation and p53 Expression: Clonal Origins of a Rare Disease

Castleman disease (CD) is a rare lymphoproliferative disorder with distinct clinical subtypes. However, our understanding of the underlying pathogenesis of particular subtypes of CD remains unclear. While the characteristic morphologic changes within UCD, including occasional cases of overgrowth of...

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Bibliographic Details
Main Authors: Kunwar I. Singh, Sumanth Gollapudi, Jyoti Kumar, Alexandra Butzmann, Corinn Small, Sara Kreimer, Emine Arzu Saglam, Roger Warnke, Oscar Silva, Robert S. Ohgami
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
Castleman disease
PDGFRB
TP53
p53
fibroblastic reticular cell
follicular dendritic cell
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.857606/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.857606/full

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