Multi-omics profiling of single nuclei from frozen archived postmortem human pituitary tissue

Multi-omics profiling of single nuclei from frozen archived postmortem human pituitary tissue

Summary: Concomitant profiling of transcriptome and chromatin accessibility in isolated nuclei can reveal gene regulatory control mechanisms in health and disease. We report a single nucleus multi-omics analysis protocol optimized for frozen archived postmortem human pituitaries that is also effecti...

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Bibliographic Details
Main Authors: Natalia Mendelev, Michel Zamojski, Mary Anne S. Amper, Wan Sze Cheng, Hanna Pincas, Venugopalan D. Nair, Elena Zaslavsky, Stuart C. Sealfon, Frederique Ruf-Zamojski
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:STAR Protocols
Subjects:
Cell Biology
Single Cell
Health Sciences
Genomics
Sequencing
RNAseq
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722003264

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http://www.sciencedirect.com/science/article/pii/S2666166722003264

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