Multi-omics profiling of single nuclei from frozen archived postmortem human pituitary tissue

Multi-omics profiling of single nuclei from frozen archived postmortem human pituitary tissue

Summary: Concomitant profiling of transcriptome and chromatin accessibility in isolated nuclei can reveal gene regulatory control mechanisms in health and disease. We report a single nucleus multi-omics analysis protocol optimized for frozen archived postmortem human pituitaries that is also effecti...

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Bibliographic Details
Main Authors:	Natalia Mendelev, Michel Zamojski, Mary Anne S. Amper, Wan Sze Cheng, Hanna Pincas, Venugopalan D. Nair, Elena Zaslavsky, Stuart C. Sealfon, Frederique Ruf-Zamojski
Format:	Article
Language:	English
Published:	Elsevier 2022-06-01
Series:	STAR Protocols
Subjects:	Cell Biology Single Cell Health Sciences Genomics Sequencing RNAseq
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666166722003264

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