Impact of SGLT-2 Inhibition on Cardiometabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome

Impact of SGLT-2 Inhibition on Cardiometabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-age women. PCOS is characterized by hyperandrogenism and ovulatory dysfunction. Women with PCOS have a high prevalence of obesity, insulin resistance (IR), increased blood pressure (BP), and activation of the reni...

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Bibliographic Details
Main Authors: Jacob E. Pruett, Edgar D. Torres Fernandez, Steven J. Everman, Ruth M. Vinson, Kacey Davenport, Madelyn K. Logan, Stephanie A. Ye, Damian G. Romero, Licy L. Yanes Cardozo
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
polycystic ovary syndrome
androgens
obesity
renin-angiotensin system
blood pressure
sodium glucose cotransporter-2
Online Access:https://www.mdpi.com/1422-0067/22/5/2576

Internet

https://www.mdpi.com/1422-0067/22/5/2576

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