Advanced Maternal Age Impairs Uterine Artery Adaptations to Pregnancy in Rats

Advanced Maternal Age Impairs Uterine Artery Adaptations to Pregnancy in Rats

Advanced maternal age (≥35 years) is associated with pregnancy complications. Aging impairs vascular reactivity and increases vascular stiffness. We hypothesized that uterine artery adaptations to pregnancy are impaired with advanced age. Uterine arteries of nonpregnant and pregnant (gestational day...

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Bibliographic Details
Main Authors: Amy L. Wooldridge, Mazhar Pasha, Palehswan Chitrakar, Raven Kirschenman, Anita Quon, Floor Spaans, Tamara Sáez, Christy-Lynn M. Cooke, Sandra T. Davidge
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
advanced maternal age
uterine artery
pregnancy
myogenic response
circumferential stress-strain
arterial structure
Online Access:https://www.mdpi.com/1422-0067/23/16/9191

Internet

https://www.mdpi.com/1422-0067/23/16/9191

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