The Role of nmcR, ampR, and ampD in the Regulation of the Class A Carbapenemase NmcA in Enterobacter ludwigii

Various carbapenemases have been identified in the Enterobacteriaceae. However, the induction and corresponding regulator genes of carbapenemase NmcA has rarely been detected in the Enterobacter cloacae complex (ECC). The NmcA-positive isolate ECC NR1491 was first detected in Japan in 2013. It was c...

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Main Authors: Ryuichi Nakano, Yuki Yamada, Akiyo Nakano, Yuki Suzuki, Kai Saito, Ryuji Sakata, Miho Ogawa, Kazuya Narita, Akio Kuga, Akira Suwabe, Hisakazu Yano
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.794134/full