Clinical and molecular correlation defines activity of physiological pathways in life-sustaining kidney xenotransplantation

Abstract Porcine kidney xenotransplantation is accelerating towards clinical translation. However, despite the demonstrated ability of porcine kidneys to remove metabolic waste products, questions remain about their ability to faithfully recapitulate renal endocrine functions after transplantation....

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Bibliographic Details
Main Authors: Daniel J. Firl, Grace Lassiter, Takayuki Hirose, Robert Policastro, Ashley D’Attilio, James F. Markmann, Tatsuo Kawai, Katherine C. Hall
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38465-x