Radiomics of metastatic brain tumor as a predictive image biomarker of progression-free survival in patients with non-small-cell lung cancer with brain metastasis receiving tyrosine kinase inhibitors

Radiomics of metastatic brain tumor as a predictive image biomarker of progression-free survival in patients with non-small-cell lung cancer with brain metastasis receiving tyrosine kinase inhibitors

Background and objective: Epidermal growth factor receptor (EGFR)–targeted tyrosine kinase inhibitors (TKIs) are the first-line therapy for EGFR-mutant non-small-cell lung cancer (NSCLC). Early prediction of treatment failure in patients with brain metastases treated with EGFR–TKIs may help in makin...

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Bibliographic Details
Main Authors: Ting-Wei Wang, Heng-Sheng Chao, Hwa-Yen Chiu, Chia-Feng Lu, Chien-Yi Liao, Yen Lee, Jyun-Ru Chen, Tsu-Hui Shiao, Yuh-Min Chen, Yu-Te Wu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Translational Oncology
Subjects:
Non-small-cell lung cancer with brain metastasis
Epidermal growth factor receptor–tyrosine kinase inhibitors
Treatment outcome prediction
Radiomics
Deep learning
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323002127

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http://www.sciencedirect.com/science/article/pii/S1936523323002127

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