ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders

The liver, pancreas, and heart are particularly susceptible to iron-related disorders. These tissues take up plasma iron from transferrin or non-transferrin-bound iron, which appears during iron overload. Here, we assessed the effect of iron status on the levels of the transmembrane transporters, ZR...

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Bibliographic Details
Main Authors: Hyeyoung Nam, Chia-Yu Wang, Lin Zhang, Wei Zhang, Shintaro Hojyo, Toshiyuki Fukada, Mitchell D. Knutson
Format: Article
Language:English
Published: Ferrata Storti Foundation 2013-07-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6714