Nicotine promotes tumor growth and metastasis in mouse models of lung cancer.

Nicotine is the major addictive component of tobacco smoke. Although nicotine is generally thought to have limited ability to initiate cancer, it can induce cell proliferation and angiogenesis in a variety of systems. These properties might enable nicotine to facilitate the growth of tumors already...

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Bibliographic Details
Main Authors: Rebecca Davis, Wasia Rizwani, Sarmistha Banerjee, Michelle Kovacs, Eric Haura, Domenico Coppola, Srikumar Chellappan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2759510?pdf=render