Early cytokine signatures and clinical phenotypes discriminate persistent from resolving MRSA bacteremia

Early cytokine signatures and clinical phenotypes discriminate persistent from resolving MRSA bacteremia

Abstract Background Staphylococcus aureus bacteremia (SAB) is a prevalent life-threatening infection often caused by methicillin-resistant S. aureus (MRSA). Up to 30% of SAB patients fail to clear infection even with gold-standard anti-MRSA antibiotics. This phenomenon is termed antibiotic-persisten...

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Bibliographic Details
Main Authors: Kristina V. Bergersen, Ying Zheng, Maura Rossetti, Felicia Ruffin, Harry Pickering, Rajesh Parmar, Gemalene Sunga, Liana C. Chan, David Gjertson, Vance G. Fowler, Michael R. Yeaman, Elaine F. Reed, the MRSA Systems Immunobiology Group
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Infectious Diseases
Subjects:
Staphylococcus aureus
MRSA
Cytokine signatures
Clinical phenotypes
Persistence
Online Access:https://doi.org/10.1186/s12879-025-10620-3

Internet

https://doi.org/10.1186/s12879-025-10620-3

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