Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells.

Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells.

The active hormonal form of vitamin D, 1,25-dihydroxyvitamin D (1,25D) is an important modulator of the immune system, inhibiting cellular proliferation and regulating transcription of immune response genes. In order to characterize the genetic basis of variation in the immunomodulatory effects of 1...

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Bibliographic Details
Main Authors: Silvia N Kariuki, Joseph C Maranville, Shaneen S Baxter, Choongwon Jeong, Shigeki Nakagome, Cara L Hrusch, David B Witonsky, Anne I Sperling, Anna Di Rienzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4959717?pdf=render

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http://europepmc.org/articles/PMC4959717?pdf=render

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