Amphioxus adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U and A-to-I deamination of DNA

Amphioxus adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U and A-to-I deamination of DNA

Abstract Adenosine-to-inosine tRNA-editing enzyme has been identified for more than two decades, but the study on its DNA editing activity is rather scarce. We show that amphioxus (Branchiostoma japonicum) ADAT2 (BjADAT2) contains the active site ‘HxE-PCxxC’ and the key residues for target-base-bind...

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Bibliographic Details
Main Authors: Zhan Gao, Wanyue Jiang, Yu Zhang, Liping Zhang, Mengmeng Yi, Haitao Wang, Zengyu Ma, Baozhen Qu, Xiaohan Ji, Hongan Long, Shicui Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05134-0

Internet

https://doi.org/10.1038/s42003-023-05134-0

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